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It was found out that naltrexone and bupropion combined, which may be marketed later on as Contrave, provide better weight loss results than exercise and dieting alone.
Using two separate drugs to lose weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the those who go through it you need to err to the side of caution and allow the FDA do its job and demand some study be done so your public is aware of the side effects and hazards of the medications before we drive them. Keep in mind that drug companies are in business to generate income and that they would say everything to keep people on his or her medications.
Researchers found out that participants taking this drug for a year, lost excess weight within four weeks and have kept the weight off through the 56 weeks from the study. Contrave is really a combination with the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which are made up of more than one active ingredient, which might make them more effective and safer.
Combo-pilling may be the newest fad or also the newest in the future under scrutiny and so it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular could be the fact that at the time of right now there aren't long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be authorized by the FDA.
Seizures certainly are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug could also raise blood pressure and pulse rate, and shouldn't be used in people who have a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug.
The FDA also warned that Contrave can raise blood pressure level and pulse rate and must not used in patients with uncontrolled high hypertension, as well as by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients which has a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients towards the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking.
"This could be the first drug I'm aware of that targets the two appetite and reward centres in the brain," he was quoted saying.